Pre+Pro+Post Biotic Gut Health Solution

Tri-Biome

Improve Digestion & Regularity
Pre+Pro+Post Biotic Gut Health Solution

Tri-Biome

Improve Digestion & Regularity

Still bloated or backed up after trying another probiotic? Most probiotics stop at adding bacteria. Tri-Biome takes a more complete approach, combining probiotics, prebiotics, and postbiotics to support your gut from multiple angles. To take that support a step further, Akkermansia muciniphila and CoreBiome® Tributyrin help support the gut barrier and create a healthier environment for your microbiome. If a basic probiotic hasn’t done much for you, it may be time for something more complete.

  • Less bloating, more regularity — 10 Billion CFU across 10 strains†
  • Fixes digestion at the source — the full pre+pro+postbiotic system, not just probiotics†
  • Repairs your gut lining — with Akkermansia muciniphila + CoreBiome® Tributyrin†
  • 2 capsules a day, no fridge, no extra bottles†
$ 54.99or as low as $38.49/bottle with a subscription
See the Data
Try UMZU risk-free — 60-day money-back guarantee

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The Tri-Biome System

Three Functions. One formula.

Tri-Biome combines prebiotics, probiotics and postbiotics into one complete approach to daily gut support.

Scroll to explore ↓
01 Prebiotic

Feed the good bacteria.

Before you can support a healthy gut, you need to support the beneficial bacteria already living there.

Key ingredient 250 mg
Inaveaâ„¢ Prebiotic Fiber
Organic Baobab + Acacia
Explore the science +

Prebiotics are the fuel your good bacteria thrive on. Tri-Biome uses Inaveaâ„¢, an organic fiber blend of baobab and acacia, to feed the beneficial bacteria already living in your gut.

A well-fed microbiome gives the probiotic layer a better environment to work in and supports balanced digestion over time.

02 Probiotic

Populate the microbiome.

Tri-Biome combines clinically studied probiotic strains with 10 billion CFU to support a diverse gut microbiome.

Key ingredient 10B CFU
Probiotic Blend
Clinically studied strains
Explore the science +

Probiotics add beneficial bacteria directly to your gut. Tri-Biome delivers 9 targeted strains, including Akkermansia, at 10 billion CFU.

A delayed-release capsule helps protect the live cultures from stomach acid, so more of them can reach the gut where they do their work.

03 Postbiotic

Support the gut barrier.

CoreBiome® Tributyrin is designed to deliver a stable source of butyrate to support the gut environment.

Key ingredient 300 mg
CoreBiome® Tributyrin
Targeted postbiotic support
Explore the science +

Postbiotics are the beneficial compounds your gut bacteria produce. CoreBiome® Tributyrin provides a stable source of butyrate, a short-chain fatty acid that the cells lining the gut use for energy.

It supports the gut barrier and a healthy gut environment, completing the feed, populate, support formula.

Prebiotic
Probiotic
Postbiotic
GUT SCIENCE
PRE + PRO + POST
PRE + PRO + POST

2 capsules a day. One complete gut health formula.

Prebiotics, probiotics and postbiotics work together to support a balanced microbiome, healthy digestion and a stronger gut barrier.

Shop Tri-Biome →
HPMC delayed-release capsule for better probiotic delivery
How Tri-Biome Compares

More than a probiotic

Most probiotics stop at live bacteria. Tri-Biome combines organic prebiotic fiber, 9 targeted probiotic strains, and a CoreBiome® postbiotic — a complete 3-in-1 gut stack most single-ingredient formulas don't offer.†

  Tri-Biome Single biotic or fiber
9 targeted probiotic strains, including HPMC delayed-release capsule that protects live cultures from stomach acid
Delivery technology varies — most standard capsules offer no acid protection
9 targeted probiotic strains, including Akkermansia
Usually limited to 1–2 strains
Organic prebiotic fiber from Inaveaâ„¢ baobab + acacia
Prebiotic fiber is often left out entirely
9 targeted probiotic strains, including Akkermansia for gut lining & metabolic (GLP-1) support
Rarely included in gut health formulas
9 targeted probiotic strains, including CoreBiome® postbiotic for butyrate & gut-barrier support
Postbiotic support is typically missing
Complete 3-in-1: prebiotic + probiotic + postbiotic
Usually just one piece of the gut health puzzle

† Comparison reflects common single-strain probiotic or prebiotic-only formulas. Ingredients, strain counts, and features vary by product.

Inside The Formula

Four ingredients, one job

Four ingredients, one job
Tri-Biome contains 8 clinically studied probiotic strains, including species of Lactobacillus and Bifidobacterium. These strains help promote balanced digestion, improve regularity, and support overall gut health by populating the intestines with beneficial bacteria.*
Tributyrin is a postbiotic that strengthens the gut lining, supports tight junction integrity, and creates a more hospitable environment for probiotics to thrive. It also helps regulate inflammation in the gut.*
This rare probiotic supports the gut barrier, encourages healthy weight management, and has been shown to increase natural GLP-1 production — a key hormone involved in appetite and digestion.*
These plant-based prebiotic fibers feed beneficial gut bacteria and help produce short-chain fatty acids like butyrate, which fuel gut cells and improve digestive health. This helps you stay regular, naturally.
Choose Your Plan

Save more with a subscription

Cancel or modify anytime — no commitment required.

1 Bottle
Instant Savings $ 11.00
1 Bottle
$ 43.99$ 54.99
$ 43.99Per Bottle
Regularly $ 54.99
Free shipping on subscription orders
60-day money-back guarantee
2 Bottles
Instant Savings $ 27.50
2 Bottles
$ 82.48$ 109.98
$ 41.24Per Bottle
Regularly $ 109.98
Free shipping on subscription orders
60-day money-back guarantee

By selecting Subscribe & Save, you'll be enrolled in an automatic recurring subscription at the interval and price shown above. You can modify, skip, or cancel your subscription anytime from your account. †These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Natural products you can trust

with benefits you can feel.

No Harmful Fillers
Thermo-Approved
Natural Ingredients
cGMP Manufactured
Research- Backed
Assembled in the USA
Lab Tested

Two capsules a day. A number you can check.

All Three Biotics- One Formula.

Shop Tri-Biome — $ 54.99